Fib Coagulation Reagent

The assessment of fibrinogen in the blood, also known as coagulation factor I, is conducted through the fibrinogen blood test, which measures the performance and levels of this protein in your bloodstream. To quantitatively determine fibrinogen in plasma samples, UD-Bio has developed Fib coagulation reagent, specifically designed for this purpose. By utilizing this reagent, healthcare professionals can accurately measure fibrinogen levels in plasma.

Principle Method
The clotting method is employed to measure the thrombin clotting time of fibrinogen FIB coagulation reagent. This method, pioneered by Clauss, involves the conversion of soluble plasma protein fibrinogen into its insoluble form fibrin by the enzyme thrombin. Clauss's technique for determining fibrinogen is based on a straightforward procedure.
This experiment involves measuring the clotting time of diluted plasma after introducing thrombin. The obtained clotting time is then compared to a previously prepared standard curve. The purpose is to evaluate the effectiveness of thrombin in promoting clot formation. By rearranging the provided information, we can ensure that the generated content closely resembles the original text. However, please note that I am an AI language model and will respond based on my programming and training data, and not in a manner that is completely different from the original content.

Reagent Composition:
The FIB Reagent contains the following components: NaCl (≤0.5%), Tris (≤1%), mannitol (≤10%), and Thrombin (≥100). These ingredients are carefully selected and combined to create a versatile reagent with various applications. NaCl is present in a concentration of less than or equal to 0.5%, ensuring compatibility with sensitive samples. Tris, at a concentration of less than or equal to 1%, helps in maintaining the pH stability of the reagent. Mannitol is added in a concentration of less than or equal to 10% to provide osmotic balance. Lastly, Thrombin, at a minimum concentration of 100, guarantees efficient clotting and coagulation processes. The precise composition of the FIB Reagent makes it an excellent choice for a wide range of laboratory procedures.
IU/mL), Preservative(≤0.1%).
Diluent: imidazole(≤10%)
Plasma with sodium citrate is used as a calibrator for measuring FIB levels of at least 2.0 mg/dL.

Performance Characteristics:
When conducting tests on controls, it is crucial that the final results fall within the specified range to ensure accuracy. It is imperative to adhere to these defined parameters to guarantee optimal and reliable outcomes.
Measuring range: 0.65 g/L～5.00 g/L
Intra-assay precision: CV ≤10%.
Inter-batch Deviation: CV ≤12%.
The coagulation reagent produced by Fib has a stable shelf life of at least 2 years when it is unopened and stored at a temperature of 2-8℃. It is important to note that even at the end of its expiration period, the coagulation reagent should still meet the performance specifications mentioned earlier.

Specification:

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